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準(zhǔn)備好,長命百歲有望成為普遍現(xiàn)象

準(zhǔn)備好,長命百歲有望成為普遍現(xiàn)象

Beth Kowitt 2015年11月05日
大數(shù)據(jù)將幫助人們破譯與衰老有關(guān)的遺傳密碼。

????醫(yī)學(xué)革命前沿領(lǐng)域的兩位頂尖科學(xué)家相信,人類的壽命或?qū)⑾蛉粩?shù)延伸。

????南加州大學(xué)藥物工程學(xué)教授大衛(wèi)·阿古斯在本周舉行的財(cái)富全球論壇上表示,他認(rèn)為依靠現(xiàn)有技術(shù),人們活到九十多、一百多歲有望成為普遍現(xiàn)象。

????基因組分析和細(xì)胞治療機(jī)構(gòu)Human Longevity Inc.首席執(zhí)行官克雷格·文特爾指出,人類壽命也許沒有理論上限,但“我們得確保地球能養(yǎng)活壽命特別長的人類”。

????究其原因,還是醫(yī)學(xué)和科技的交叉領(lǐng)域,例如大數(shù)據(jù)研究進(jìn)展迅速,抗衰老方面實(shí)現(xiàn)突破才成為可能。

????文特爾解釋說,15年前他首次確定人類基因組排序時(shí)沒有任何可供參考對象。而現(xiàn)在我們知道,人們從父母那里得到的64億對DNA中,有大約3%會發(fā)生變異。

????文特爾表示,10年前絕想不到有一天我們能根據(jù)遺傳密碼來預(yù)測壽命。現(xiàn)在,我們還知道人類的遺傳密碼一直在變化。比如說,男性會從40多歲或50多歲開始失去y染色體。

????為了破解信息量巨大的遺傳密碼,文特爾說他和他的團(tuán)隊(duì)聘請了設(shè)計(jì)谷歌翻譯的工程師:“我們正在讓機(jī)器進(jìn)行學(xué)習(xí),目的是理解和詮釋所有數(shù)據(jù)?!彼f,現(xiàn)在他們已經(jīng)有能力根據(jù)一個(gè)人的遺傳密碼來直接生成此人的照片。

????那么,掌握了這些數(shù)據(jù)就能自動延長人類壽命嗎?實(shí)際情況要更復(fù)雜一些。

????阿古斯說:“人類每六個(gè)月都會習(xí)得新特質(zhì),正是這些特質(zhì)讓人類變得越發(fā)復(fù)雜?!边@同時(shí)意味著,我們永遠(yuǎn)也無法完全理解疾病的原理,不過阿古斯補(bǔ)充道,控制疾病并不一定需要理解它。

譯者:Charlie

審校:夏林

????Two of the leading scientists at the edge of the medical revolution believe that our life expectancy could start creeping up toward the triple digits.

????David Agus, a professor of medicine and engineering at the University of Southern California, said at the Fortune Global Forum on Monday that he believes that with our current technology humans have the potential to regularly live into their ninth or tenth decade.

????Craig Venter, co-founder and CEO of Human Longevity Inc., said there might be no hypothetical limit to how long we can live, but that “we need to make sure we can support extra long life on this planet.”

????Huge advancements at the intersection of medicine and technology, such as big data, are making these kinds of developments in aging possible.

????Venter explained that when he first sequenced the human genome 15 years ago, there was nothing for him to compare it to. For example, we now know that we vary about 3% from the 6.4 billion letters of DNA that we get from our parents.

????Ten years ago, Venter said he wouldn’t have thought that we’d be able to predict someone’s age from their genetic code. We also now know that our genetic code is constantly changing, he said. Men, for example, start losing y chromosomes in their 40s and 50s.

????To help crack the big data code in medicine, Venter said he and his team have hired the engineer who designed Google Translate. “We’re using machine learning to try to understand and interpret all that data,” he explained. He said that they now have the capability to generate a photo of someone straight from their genetic code.

????So will all this data automatically extend our lifespan. That’s a bit more complicated.

????“We’re learning new dimensions to each of us every six months,” Agus said. “These dimensions make us more complex.” That means we’re never going to totally understand disease, he added, but we don’t need to understand it to control it.

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