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大數(shù)據(jù)能治愈癌癥嗎?

大數(shù)據(jù)能治愈癌癥嗎?

Erika Fry 2016年11月07日
“白宮抗癌登月計(jì)劃特別小組”的執(zhí)行董事沒有抱太大期望。

盡管大數(shù)據(jù)有潛力治愈癌癥的言論甚囂塵上,但“白宮抗癌登月計(jì)劃特別小組”(White House’s Cancer Moonshot Taskforce)的執(zhí)行董事格雷格·西蒙對(duì)此表示懷疑——至少現(xiàn)在不行。

上周三在圣迭戈的《財(cái)富》頭腦風(fēng)暴健康大會(huì)上,西蒙問道:“什么大數(shù)據(jù)?我們的健康系統(tǒng)里面有數(shù)據(jù),基本上僅供內(nèi)部交流使用。我知道一些你們不知道的。你們也知道一些我不知道的。如果我需要知道你們知道的,我就會(huì)給你們打電話,發(fā)郵件。你們則會(huì)把信息傳給我?!?/p>

他繼續(xù)道:“大數(shù)據(jù)是人人都喜歡的熱門概念。但在醫(yī)療領(lǐng)域,我們的信息仍然十分匱乏?!彼赋?,盡管早在20世紀(jì)20年代,美國(guó)就建立了記錄每一筆股票交易的數(shù)據(jù)庫,但許多病人甚至現(xiàn)在都沒有自己的個(gè)人醫(yī)療記錄。

西蒙的機(jī)構(gòu)正是許多致力于解放醫(yī)療數(shù)據(jù)的組織之一。今年6月,美國(guó)建立了儲(chǔ)存基因組和臨床數(shù)據(jù),供研究者使用的數(shù)據(jù)庫Genomic Data Commons。對(duì)此,他認(rèn)為成效一般。數(shù)據(jù)庫如今從癌癥和腫瘤基因圖譜(Cancer Genome Atlas)處獲得了3.2萬人的原始基因組數(shù)據(jù)——這比6月建立時(shí)的1.4萬人已經(jīng)多出許多,而且很快就將收入幾十萬人的數(shù)據(jù)。而自6月以來,這些數(shù)據(jù)的訪問量已經(jīng)達(dá)到50億次。

西蒙把這個(gè)稱為“好消息”。壞消息呢?美國(guó)政府建立癌癥和腫瘤基因圖譜時(shí),投入了1億美元從5萬人處獲取數(shù)據(jù)。然而,其中2.4萬人的數(shù)據(jù)如今已經(jīng)不可用了。

西蒙表示:“所以,大數(shù)據(jù)目前就像壞數(shù)據(jù)。數(shù)據(jù)庫在建立時(shí),沒有依照病理學(xué)和醫(yī)學(xué)標(biāo)準(zhǔn),也不像我們收集財(cái)經(jīng)和天氣數(shù)據(jù)一樣,隨時(shí)隨地都有數(shù)據(jù)傳來?!?/p>

他也談到了大數(shù)據(jù)在抗擊癌癥上的前景:“它會(huì)起到作用嗎?會(huì)的。但是我們必須改變信息共享的文化,因?yàn)槲覀児蚕硇畔⒌膽B(tài)度,已經(jīng)遠(yuǎn)遠(yuǎn)落后于我們共享信息的能力?!保ㄘ?cái)富中文網(wǎng))

作者:Erika Fry

譯者:嚴(yán)匡正

While there’s a lot of breathless talk about the potential of big data to do just that, Greg Simon, the Executive Director of the White House’s Cancer Moonshot Taskforce, is a skeptic—at least for now.

“What big data?” asked Simon speaking at Fortune’s Brainstorm Health conference in San Diego Wednesday. “We have in the health system, what is basically insider trading. I know something you don’t know. You know something I don’t know. When I need to know what you know, I call you, I email you. You fax me stuff.”

He continued: “Big data is the big yellow object that everyone is in love with. But we still live in an information scarce medical world.” He noted that while the U.S. has a database of every stock transaction dating back to the 1920s, many patients can’t even liberate their own personal medical records.

His organization is one of many working to make medical data free (or freer). And of the Genomic Data Commons, a database introduced in June to pool genomic and clinical data and make it available to researchers, he reports modest success. The Commons now holds the raw genomic data, from the Cancer Genome Atlas, of 32,000 people—up from 14,000 at its June launch (it will soon be several hundred thousand people). And that data has been accessed 5 billion times since June.

Simon qualified that as “the good news.” The bad? When the government launched the Cancer Genome Atlas, it spent $100 million to get data from 50,000 people. Of that, data from 24,000 people was unusable, he said.

“So big data is in the middle of bad data—which is being created by a lack pathology and medical standards, and the lack of ubiquitous, instant data transmission like we do with financial and weather data,” Simon said.

He added of big data’s prospects in tackling cancer: “Can it make a difference? Yes. But we have to change the culture of sharing information, because our ability to share has far outpaced our attitude about sharing it.”

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