輝瑞的合作伙伴BioNTech有意在本月展開(kāi)測(cè)試,以確定其新型疫苗能否更好地預(yù)防傳染性更強(qiáng)的德?tīng)査兎N。
這次臨床試驗(yàn)的結(jié)果預(yù)計(jì)將在第四季度出爐,其中還將測(cè)試“混打”針對(duì)德?tīng)査兎N的疫苗和針對(duì)最初發(fā)現(xiàn)的“野生型”病毒的疫苗是否有效。
如果試驗(yàn)數(shù)據(jù)證明該疫苗能產(chǎn)生免疫所需的抗體反應(yīng),BioNTech 預(yù)計(jì),該公司可以在100天內(nèi)投入生產(chǎn)。由于新疫苗的生產(chǎn)線用的是和以前一樣的原材料和廠房設(shè)備,它要做的就是根據(jù)病毒變種后的不同基因序列,更改其中的DNA模型。
然而,就目前而言,這家德國(guó)生物技術(shù)公司建議對(duì)現(xiàn)有疫苗注射第三針加強(qiáng)針。研究表明,當(dāng)前的疫苗在預(yù)防因感染德?tīng)査茸兎N病毒而導(dǎo)致的重癥和死亡率方面,仍然非常有效。
周一,BioNTech首席執(zhí)行官烏古爾?薩欣(Ugur Sahin)在公司季度財(cái)報(bào)電話會(huì)議上對(duì)投資者說(shuō):“我們認(rèn)為,目前應(yīng)對(duì)變種病毒的最佳方法是繼續(xù)注射現(xiàn)在針對(duì)原始型毒株的加強(qiáng)針,”他還援引證據(jù)表明,在針對(duì)南非首次發(fā)現(xiàn)的貝塔變種中,加強(qiáng)針的效力已經(jīng)得到了證明。
輝瑞/BioNTech的對(duì)家Moderna也使用mRNA技術(shù)制造新冠疫苗,該公司同樣建議注射第三劑加強(qiáng)針。他們也在開(kāi)展一些關(guān)于“混打疫苗”的有效性的試驗(yàn)。然而,世界衛(wèi)生組織最近呼吁暫停加強(qiáng)針的注射,以便先把疫苗給到那些較貧窮的國(guó)家,讓他們趕上疫苗接種進(jìn)度。
一年前,作為全球第一家研發(fā)出有效的新冠疫苗的公司,BioNTech的股價(jià)一度飆升14% 至442.71歐元,此前,該公司報(bào)告稱,他們?cè)谏习肽甑膬羰杖霃?.42億歐元的虧損躍升至 39億歐元(46億美元)的盈利。
BioNTech的收入能猛增100多倍,達(dá)到74億歐元,主要得益于合作伙伴輝瑞付的錢,是輝瑞將其研發(fā)的疫苗分銷到世界大部分地區(qū)。本月早些時(shí)候,有報(bào)道稱,這家美國(guó)制藥商將提高BioNTech疫苗在歐洲的價(jià)格。
而B(niǎo)ioNTech僅能在德國(guó)和土耳其直接銷售自己研發(fā)的疫苗——德國(guó)是該公司創(chuàng)始人夫婦被領(lǐng)養(yǎng)的地方,土耳其則是他們的祖國(guó)。
BioNTech將與其全球分銷伙伴輝瑞和復(fù)星一起,預(yù)計(jì)將在今年出貨30億劑疫苗,明年的出貨量將為40億劑。
該公司還承諾,將在未來(lái)18個(gè)月內(nèi)向中低收入的國(guó)家提供超過(guò)20億劑疫苗。(財(cái)富中文網(wǎng))
編譯:陳聰聰
輝瑞的合作伙伴BioNTech有意在本月展開(kāi)測(cè)試,以確定其新型疫苗能否更好地預(yù)防傳染性更強(qiáng)的德?tīng)査兎N。
這次臨床試驗(yàn)的結(jié)果預(yù)計(jì)將在第四季度出爐,其中還將測(cè)試“混打”針對(duì)德?tīng)査兎N的疫苗和針對(duì)最初發(fā)現(xiàn)的“野生型”病毒的疫苗是否有效。
如果試驗(yàn)數(shù)據(jù)證明該疫苗能產(chǎn)生免疫所需的抗體反應(yīng),BioNTech 預(yù)計(jì),該公司可以在100天內(nèi)投入生產(chǎn)。由于新疫苗的生產(chǎn)線用的是和以前一樣的原材料和廠房設(shè)備,它要做的就是根據(jù)病毒變種后的不同基因序列,更改其中的DNA模型。
然而,就目前而言,這家德國(guó)生物技術(shù)公司建議對(duì)現(xiàn)有疫苗注射第三針加強(qiáng)針。研究表明,當(dāng)前的疫苗在預(yù)防因感染德?tīng)査茸兎N病毒而導(dǎo)致的重癥和死亡率方面,仍然非常有效。
周一,BioNTech首席執(zhí)行官烏古爾?薩欣(Ugur Sahin)在公司季度財(cái)報(bào)電話會(huì)議上對(duì)投資者說(shuō):“我們認(rèn)為,目前應(yīng)對(duì)變種病毒的最佳方法是繼續(xù)注射現(xiàn)在針對(duì)原始型毒株的加強(qiáng)針,”他還援引證據(jù)表明,在針對(duì)南非首次發(fā)現(xiàn)的貝塔變種中,加強(qiáng)針的效力已經(jīng)得到了證明。
輝瑞/BioNTech的對(duì)家Moderna也使用mRNA技術(shù)制造新冠疫苗,該公司同樣建議注射第三劑加強(qiáng)針。他們也在開(kāi)展一些關(guān)于“混打疫苗”的有效性的試驗(yàn)。然而,世界衛(wèi)生組織最近呼吁暫停加強(qiáng)針的注射,以便先把疫苗給到那些較貧窮的國(guó)家,讓他們趕上疫苗接種進(jìn)度。
一年前,作為全球第一家研發(fā)出有效的新冠疫苗的公司,BioNTech的股價(jià)一度飆升14% 至442.71歐元,此前,該公司報(bào)告稱,他們?cè)谏习肽甑膬羰杖霃?.42億歐元的虧損躍升至 39億歐元(46億美元)的盈利。
BioNTech的收入能猛增100多倍,達(dá)到74億歐元,主要得益于合作伙伴輝瑞付的錢,是輝瑞將其研發(fā)的疫苗分銷到世界大部分地區(qū)。本月早些時(shí)候,有報(bào)道稱,這家美國(guó)制藥商將提高BioNTech疫苗在歐洲的價(jià)格。
而B(niǎo)ioNTech僅能在德國(guó)和土耳其直接銷售自己研發(fā)的疫苗——德國(guó)是該公司創(chuàng)始人夫婦被領(lǐng)養(yǎng)的地方,土耳其則是他們的祖國(guó)。
BioNTech將與其全球分銷伙伴輝瑞和復(fù)星一起,預(yù)計(jì)將在今年出貨30億劑疫苗,明年的出貨量將為40億劑。
該公司還承諾,將在未來(lái)18個(gè)月內(nèi)向中低收入的國(guó)家提供超過(guò)20億劑疫苗。(財(cái)富中文網(wǎng))
編譯:陳聰聰
Pfizer partner BioNTech aims to begin tests this month to determine if an altered form of its COVID-19 vaccine can better protect against the far more contagious Delta variant.
The clinical trial, whose results are anticipated in the fourth quarter, will also examine whether a combination of jabs that includes an inoculation against Delta and the original “wild type” proves effective.
Should the data confirm the desired antibody response, BioNTech expects it can adapt production within 100 days. Since the same raw materials and factory equipment are employed, all it needs to do is swap out the DNA template to account for a different genetic sequence in the spike protein.
For now, however, the German biotech firm recommends a third booster shot of the existing vaccine. Studies indicate that the current vaccines are still highly effective in preventing hospitalizations and deaths from COVID-19 variants like Delta.
“We believe the best approach at the moment to deal with the situation is to continue with a booster dose with the existing wild type strain,” chief executive U?ur ?ahin told investors on Monday during a quarterly earnings call, citing evidence that it already proved effective against the Beta variant first discovered in South Africa.
Rival vaccine maker Moderna, which also uses messenger RNA to produce antibodies, likewise recommends a third vaccination. There are also trials underway on the effectiveness of mixing and matching vaccines for boosters. However, the World Health Organization recently called for a moratorium on booster shots, to allow poorer nations to catch up on vaccines.
Shares in BioNTech, the first company worldwide to develop an effective inoculation against the coronavirus, surged 14% to €442.71 after it reported that its net income for the first half swung to €3.9 billion ($4.6 billion) from a loss of €142 million a year earlier.
Revenue surged more than 100-fold to €7.4 billion primarily thanks to payments from partner Pfizer, which distributes the vaccine it created to most parts of the world. Earlier this month reports emerged that the U.S. drugmaker would raise the price of the BioNTech vaccine for Europe.
BioNTech itself markets its own treatment directly only in Germany and Turkey, the adopted and native homes respectively of the husband-and-wife pair that founded the company.
Together with global distributor partners Pfizer and Fosun, BioNTech expects to ship 3 billion doses this year and 4 billion in the next.
It has committed to delivering over 2 billion doses to low- and middle-income nations over the next 18 months.